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dr. T.G.W. (Tom) Letteboer

dr. T.G.W. (Tom) Letteboer

Assistant Professor - medical

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Research Output (54)

The effect of genotypes and parent of origin on cancer risk and age of cancer development in PMS2 mutation carriers

Suerink Manon, van der Klift Heleen M, Ten Broeke Sanne W, Dekkers Olaf M, Bernstein Inge, Capellá Munar Gabriel, Gomez Garcia Encarna, Hoogerbrugge Nicoline, Letteboer Tom G W, Menko Fred H, Lindblom Annika, Mensenkamp Arjen, Moller Pal, van Os Theo A, Rahner Nils, Redeker Bert J W, Olderode Maran, Spruijt Liesbeth, Vos Yvonne J, Wagner Anja, Morreau Hans, Hes Frederik J, Vasen Hans F A, Tops Carli M, Wijnen Juul T, Nielsen Maartje Apr 2016, In: Genetics in Medicine. 18 , p. 405–409

CORRIGENDUM: The effect of genotypes and parent of origin on cancer risk and age of cancer development in PMS2 mutation carriers

Suerink Manon, Van Der Klift Heleen M., Ten Broeke Sanne W., Dekkers Olaf M., Bernstein Inge, Munar Gabriel Capell, Gomez Garcia Encarna, Hoogerbrugge Nicoline, Letteboer Tom G W, Menko Fred H., Lindblom Annika, Mensenkamp Arjen, Moller Pal, Van Os Theo A., Rahner Nils, Redeker Bert J W, Olderode-Berends M. J W, Spruijt Liesbeth, Vos Yvonne J., Wagner Anja, Morreau Hans, Hes Frederik J., Vasen Hans F A, Tops Carli M., Wijnen Juul T., Nielsen Maartje 1 Jan 2016, In: Genetics in Medicine. 18 , p. 108 1 p.

Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients

Jansen Anne M L, Geilenkirchen Marije A, van Wezel Tom, Jagmohan-Changur Shantie C, Ruano Dina, van der Klift Heleen M, van den Akker Brendy E W M, Laros Jeroen F J, van Galen Michiel, Wagner Anja, Letteboer Tom G W, Gómez-García Encarna B, Tops Carli M J, Vasen Hans F, Devilee Peter, Hes Frederik J, Morreau Hans, Wijnen Juul T 2016, In: PLoS ONE [E]. 11

Targeted locus amplification for targeted re-sequencing of the ENG, ACVRL1 and SMAD4 genes in hereditary hemorrhagic telangiecstasia

Ploos van Amstel J. K., de Vree P. J. P., Elzo de Wit E., Marjon J. Verstegen M. J., Westermann C. J. J., Snijder R. J., Letteboer T. G. W., Mager J. J., de Laat W. Oct 2015, In: Angiogenesis. 18 , p. 570 1 p.

Lynch syndrome caused by germline PMS2 mutations:Delineating the cancer risk

Ten Broeke Sanne W., Brohet Richard M., Tops Carli M., Van Der Klift Heleen M., Velthuizen Mary E., Bernstein Inge, Munar Gabriel Capellá, Garcia Encarna Gomez, Hoogerbrugge Nicoline, Letteboer Tom G W, Menko Fred H., Lindblom Annika, Mensenkamp Arjen R., Moller Pal, Van Os Theo A., Rahner Nils, Redeker Bert J W, Sijmons Rolf H., Spruijt Liesbeth, Suerink Manon, Vos Yvonne J., Wagner Anja, Hes Frederik J., Vasen Hans F., Nielsen Maartje, Wijnen Juul T. 1 Feb 2015, In: Journal of Clinical Oncology. 33 , p. 319-325 7 p.

Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14

Letteboer Tom G W, Benzinou Michael, Merrick Christopher, Quigley David, Zhau Kechen, Kim Il Jin, To Minh D., Jablons David, Van Amstel Johannes Kristian Ploos, Westermann Cornelius, Giraud Sophie, Dupuis-Girod Sophie, Lesca Gaetan, Berg Jonathan, Balmain Allan, Akhurst Rosemary J. 1 Jan 2015, In: Frontiers in Genetics [E]. 5 9 p.

Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans

Kawasaki K., Freimuth J., Meyer D.S., Lee M.M., Tochimoto-Okamotoa A., Benzinou M., Clermont F.F., Wu G., Roy R., Letteboer T.G.W., Ploos van Amstel J.K., Giraud S., Dupuis-Girod S., Lesca G., Westermann C.J.J., Coffey, Jr R.J., Akhurst R.J. 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111 , p. 7723-7728 6 p.

Adherence to microsatellite instability testing in young-onset colorectal cancer patients

Kessels Koen, Fidder Herma H, de Groot Nicolette L, Letteboer Tom G, Timmer Robin, van Dalen Thijs, Consten Esther C, Offerhaus G Johan A, Siersema Peter D Jul 2013, In: Diseases of the Colon & Rectum. 56 , p. 825-33 9 p.

Recording of family history is associated with colorectal cancer stage

Kessels Koen, de Groot Nicolette L, Fidder Herma H, Timmer Robin, Stolk Mark F J, Offerhaus G Johan A, Siersema Peter D, , Letteboer TGW, Leenders M.B. Apr 2013, In: European Journal of Gastroenterology and Hepatology. 25 , p. 482-487 6 p.

Polymorphisms in ACVRL1 and Endoglin Genes are Not Associated with Sporadic and HHT-Related Brain AVMs in Dutch Patients

Boshuisen K., Brundel M., de Kovel C.G.F., Letteboer T.G.W., Rinkel G.J.E., Westermann C.J.J., Kim H., Pawlikowska L., Koeleman B.P.C., Klijn C.J.M. 2013, In: Translational Stroke Research. 4 , p. 375-378 4 p.

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