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prof. dr. F.W. (Folkert) Asselbergs

Full Professor
prof. dr. F.W. (Folkert) Asselbergs
  • Division of Heart & Lungs

Research Programs

Circulatory Health

Biography

Biography

Prof Folkert W. Asselbergs is Prof in cardiovascular genetics and consultant cardiologist at the department of Cardiology, University Medical Center Utrecht, Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Health Informatics, University College London, Director BRC Clinical Research Informatics Unit, University College London Hospital, Manager Research Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliane.nl).

 

Professor Asselbergs published more than 300 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org) are the most prominent ones. He is scientific coordinator of European IMI Bigdata@Heart consortium (www.bigdata-heart.eu). BigData@Heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insights driving drug development and personalized medicine through advanced big-data analytics. 

 

 

 

 

Side Activities

    • Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Director
    • Director Clinical Research Informatics Unit, University College London HospitalHealth Informatics, University College London
    • Medical Scientific Board Member "Deep".
    • Manager Research Center for Circulatory Health, UMC Utrecht

Fellowship and Awards

  • 2014 - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation (2014T001)

    2012 - Fellow of the European Society of Cardiology

    2010 - Clinical fellowship from the Netherlands Organisation for Health Research and Development(ZonMw grant 90700342)

    2003  - Dr. E. Dekker Scholarship of the Netherlands Heart Foundation(NHS 2003T010)

Research Output (332)

Prediction of vascular aging based on smartphone acquired PPG signals

Dall'Olio Lorenzo, Curti Nico, Remondini Daniel, Safi Harb Yosef, Asselbergs Folkert W, Castellani Gastone, Uh Hae-Won dec 2020, In: Scientific Reports. 10

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Surendran Praveen, Feofanova Elena V., Lahrouchi Najim, Ntalla Ioanna, Karthikeyan Savita, Cook James, Chen Lingyan, Mifsud Borbala, Yao Chen, Kraja Aldi T., Cartwright James H., Hellwege Jacklyn N., Giri Ayush, Tragante Vinicius, Thorleifsson Gudmar, Liu Dajiang J., Prins Bram P., Stewart Isobel D., Cabrera Claudia P., Eales James M., Akbarov Artur, Auer Paul L., Bielak Lawrence F., Bis Joshua C., Braithwaite Vickie S., Brody Jennifer A., Daw E. Warwick, Warren Helen R., Drenos Fotios, Nielsen Sune Fallgaard, Faul Jessica D., Fauman Eric B., Fava Cristiano, Ferreira Teresa, Foley Christopher N., Franceschini Nora, Gao He, Giannakopoulou Olga, Giulianini Franco, Gudbjartsson Daniel F., Guo Xiuqing, Harris Sarah E., Havulinna Aki S., Helgadottir Anna, van der Harst Pim, Vaartjes Ilonca, Asselbergs Folkert W., Bots Michiel L., van der Harst Pim, van der Meer Peter, , , , , dec 2020, In: Nature Genetics. 52 , p. 1314-1332 19 p.

Evaluating a cardiovascular disease risk management care continuum within a learning healthcare system:a prospective cohort study

Groenhof T Katrien J, Lely A Titia, Haitjema Saskia, Nathoe Hendrik M, Kortekaas Marlous F, Asselbergs Folkert W, Bots Michiel L, Hollander Monika, 17 nov 2020, In: BJGP Open. 4

Big Data and Artificial Intelligence:Opportunities and Threats in Electrophysiology

van de Leur Rutger R, Boonstra Machteld J, Bagheri Ayoub, Roudijk Rob W, Sammani Arjan, Taha Karim, Doevendans Pieter Afm, van der Harst Pim, van Dam Peter M, Hassink Rutger J, van Es René, university Folkert W nov 2020, In: Arrhythmia & electrophysiology review. 9 , p. 146-154 9 p.

Takotsubo cardiomyopathy in COVID-19:A case report. Haemodynamic and therapeutic considerations

Van Osch Dirk, Asselbergs Folkert W., Teske Arco J. 1 okt 2020, In: European Heart Journal - Case Reports. 4

Strength of patient cohorts and biobanks for cardiomyopathy research

de Boer R A, Nijenkamp L L A M, Silljé H H W, Eijgenraam T R, Parbhudayal R, van Driel B, Huurman R, Michels M, Pei J, Harakalova M, van Lint F H M, Jansen M, Baas A F, Asselbergs F W, van Tintelen J P, Brundel B J J M, Dorsch L M, Schuldt M, Kuster D W D, van der Velden J, aug 2020, In: Netherlands Heart Journal. 28 , p. 50-56 7 p.

H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts

Pei Jiayi, Harakalova Magdalena, Treibel Thomas A, Lumbers R Thomas, Boukens Bastiaan J, Efimov Igor R, van Dinter Jip T, González Arantxa, López Begoña, El Azzouzi Hamid, van den Dungen Noortje, van Dijk Christian G M, Krebber Merle M, den Ruijter Hester M, Pasterkamp Gerard, Duncker Dirk J, Nieuwenhuis Edward E S, de Weger Roel, Huibers Manon M, Vink Aryan, Moore Jason H, Moon James C, Verhaar Marianne C, Kararigas Georgios, Mokry Michal, Asselbergs Folkert W, Cheng Caroline 14 jul 2020, In: Clinical Epigenetics. 12 18 p.

Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk:Meta-Analysis of 119 Clinical Trials Involving 100,667 Patients

Willeit Peter, Tschiderer Lena, Allara Elias, Reuber Kathrin, Seekircher Lisa, Gao Lu, Liao Ximing, Lonn Eva, Gerstein Hertzel C, Yusuf Salim, Brouwers Frank P, Asselbergs Folkert W, van Gilst Wiek, Anderssen Sigmund A, Grobbee Diederick E, Kastelein John J P, Visseren Frank L J, Ntaios George, Hatzitolios Apostolos I, Savopoulos Christos, Nieuwkerk Pythia T, Stroes Erik, Walters Matthew, Higgins Peter, Dawson Jesse, Gresele Paolo, Guglielmini Giuseppe, Migliacci Rino, Ezhov Marat, Safarova Maya, Balakhonova Tatyana, Sato Eiichi, Amaha Mayuko, Nakamura Tsukasa, Kapellas Kostas, Jamieson Lisa M, Skilton Michael, Blumenthal James A, Hinderliter Alan, Sherwood Andrew, Smith Patrick J, van Agtmael Michiel A, Reiss Peter, van Vonderen Marit G A, Kiechl Stefan, Klingenschmid Gerhard, Sitzer Matthias, Stehouwer Coen D A, Blankestijn Peter J, Bots Michiel L, 17 jun 2020, In: Circulation. 142 , p. 621-642 22 p.

A registry-based algorithm to predict ejection fraction in patients with heart failure

Uijl Alicia, Lund Lars H, Vaartjes Ilonca, Brugts Jasper J, Linssen Gerard C, Asselbergs Folkert W, Hoes Arno W, Dahlström Ulf, Koudstaal Stefan, Savarese Gianluigi 17 jun 2020, In: ESC heart failure. 7 , p. 2388-2397 10 p.

All research output