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dr. ir. G.C.M. (Trudy) Straetemans

dr. ir. G.C.M. (Trudy) Straetemans

Associate Professor
  • Laboratory for Translational Immunology (LTI)
  • Department of Hematology

Research Programs

Research Output (22)

Basics of advanced therapy medicinal product development in academic pharma and the role of a GMP simulation unit

Johanna I., Daudeij A., Devina F., Nijenhuis C., Nuijen B., Romberg B., de Haar C., Haanen J., Dolstra H., Bremer E., Sebestyen Z., Straetemans T., Jedema I., Kuball J. Dec 2023, In: Immuno-Oncology and Technology. 20 9 p.

Strategies to improve γδTCRs engineered T-cell therapies for the treatment of solid malignancies

Meringa A D, Hernández-López P, Cleven A, de Witte M, Straetemans T, Kuball J, Beringer D X, Sebestyen Z 2023, In: Frontiers in Immunology. 14 , p. 1-7

Uncovering the mode of action of engineered T cells in patient cancer organoids

Dekkers Johanna F., Alieva Maria, Cleven Astrid, Keramati Farid, Wezenaar Amber K.L., van Vliet Esmée J., Puschhof Jens, Brazda Peter, Johanna Inez, Meringa Angelo D., Rebel Heggert G., Buchholz Maj Britt, Barrera Román Mario, Zeeman Amber L., de Blank Sam, Fasci Domenico, Geurts Maarten H., Cornel Annelisa M., Driehuis Else, Millen Rosemary, Straetemans Trudy, Nicolasen Mara J.T., Aarts-Riemens Tineke, Ariese Hendrikus C.R., Johnson Hannah R., van Ineveld Ravian L., Karaiskaki Froso, Kopper Oded, Bar-Ephraim Yotam E., Kretzschmar Kai, Eggermont Alexander M.M., Nierkens Stefan, Wehrens Ellen J., Stunnenberg Henk G., Clevers Hans, Kuball Jürgen, Sebestyen Zsolt, Rios Anne C. 25 Jul 2022, In: Nature Biotechnology. 41 , p. 60-69 10 p.

γ9δ2 T-Cell Expansion and Phenotypic Profile Are Reflected in the CDR3δ Repertoire of Healthy Adults

Vyborova Anna, Janssen Anke, Gatti Lucrezia, Karaiskaki Froso, Yonika Austin, van Dooremalen Sanne, Sanders Jasper, Beringer Dennis X, Straetemans Trudy, Sebestyen Zsolt, Kuball Jürgen 7 Jul 2022, In: Frontiers in Immunology. 13 , p. 1-13

The Role of γδ T Cells as a Line of Defense in Viral Infections after Allogeneic Stem Cell Transplantation:Opportunities and Challenges

Janssen Anke, van Diest Eline, Vyborova Anna, Schrier Lenneke, Bruns Anke, Sebestyen Zsolt, Straetemans Trudy, de Witte Moniek, Kuball Jürgen Jan 2022, In: Viruses. 14 , p. 1-15

Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds

Van Diest Eline, Hernández López Patricia, Meringa Angelo D., Vyborova Anna, Karaiskaki Froso, Heijhuurs Sabine, Gumathi Bormin Jan, Van Dooremalen Sanne, Nicolasen Mara J.T., Gatti Lucrezia C.D.E., Johanna Inez, Straetemans Trudy, Sebestyén Zsolt, Beringer Dennis X., Kuball Jürgen 23 Nov 2021, In: Journal for ImmunoTherapy of Cancer. 9 , p. 1-15

Adding Help to an HLA-A*24:02 Tumor-Reactive gamma delta TCR Increases Tumor Control

Johanna Inez, Hernández-López Patricia, Heijhuurs Sabine, Scheper Wouter, Bongiovanni Laura, de Bruin Alain, Beringer Dennis X., Oostvogels Rimke, Straetemans Trudy, Sebestyen Zsolt, Kuball Jürgen 25 Oct 2021, In: Frontiers in Immunology. 12 , p. 1-12

Characterization and modulation of anti-alpha beta TCR antibodies and their respective binding sites at the beta TCR chain to enrich engineered T cells

Kierkels Guido J J, van Diest Eline, Hernández-López Patricia, Scheper Wouter, de Bruin Anja C M, Frijlink Elselien, Aarts-Riemens Tineke, van Dooremalen Sanne F J, Beringer Dennis X, Oostvogels Rimke, Kramer Lovro, Straetemans Trudy, Uckert Wolfgang, Sebestyén Zsolt, Kuball Jürgen 10 Sep 2021, In: Molecular Therapy - Methods and Clinical Development. 22 , p. 388-400 13 p.

αβ T-cell graft depletion for allogeneic HSCT in adults with hematological malignancies

De Witte Moniek A., Janssen Anke, Nijssen Klaartje, Karaiskaki Froso, Swanenberg Luuk, van Rhenen Anna, Admiraal Rick, van der Wagen Lotte, Minnema Monique C., Petersen Eefke, Raymakers Reinier A.P., Westinga Kasper, Straetemans Trudy, Halkes Constantijn J.M., Boelens Jaap Jan, Kuball Jurgen 12 Jan 2021, In: Blood Advances. 5 , p. 240-249 10 p.

gamma 9 delta 2T cell diversity and the receptor interface with tumor cells

Vyborova Anna, Beringer Dennis X, Fasci Domenico, Karaiskaki Froso, van Diest Eline, Kramer Lovro, de Haas Aram, Sanders Jasper, Janssen Anke, Straetemans Trudy, Olive Daniel, Leusen Jeanette Hw, Boutin Lola, Nedellec Steven, Schwartz Samantha L, Wester Michael J, Lidke Keith A, Scotet Emmanuel, Lidke Diane, Heck Albert Jr, Sebestyen Zsolt, Kuball Jurgen 2 Jun 2020, In: Journal of Clinical Investigation. 130 , p. 4637-4651 15 p.

All research output

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