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prof. dr. J. Hendrikse

Full Professor

  • Radiology
  • Researchgr. Neuroradiologie

prof. dr. J. Hendrikse

Research Programs

Biography

The overall aim of prof. Hendrikse’s research is to understand the cause of ischemic stroke with a focus on the three P’s: Pipes (vessel and vessel walls), Perfusion (CBF and reserve capacity) and Parenchyma (brain tissue and tissue changes/infarcts). After his PhD in 2004 he has created a new research field with technical development and clinical applications of MR methods of cerebral perfusion (so called arterial spin labeling MRI) and intracranial vessel wall imaging. His original MR research is recognized by the international research field with European grants (FP7, Biocog; WP leader) and personal national excellence grants (ERC-StG, VIDI, VENI, Heart association, Technical Research Council), chairmanship of international (ISMRM) perfusion study group, steering committee member of Carotid Stenosis Triallists Collaboration (CSTC), invited lectures, reviews, white papers and book chapters. 22 of his publications are within international collaborations (including Johns Hopkins University and Vanderbilt University, USA). He has over 30 publications within the field of 7T MRI brain imaging method developments. In the radiology and neurovascular research arena ‘RADIOLOGY and ‘STROKE’ are leading journals: he has over 30 publications in these journals. He is the first radiologist awarded with a VIDI grant and an ERC-StG. The focus of his research group is to understand the relation between the ‘3Ps’: pipes (arterial vasculature), perfusion and parenchyma (brain tissue damage) by using innovative imaging methods. Early 2017 he was appointed Chairman of Radiology and Nuclear Medicine UMC Utrecht.

 

Research line

Brain MRI: Pipes, Perfusion, Parenchyma

Most recent key publications

1: Dieleman N, Van der Kolk AG. Hendrikse J. MR intracranial vessel wall imaging: current prospects and future directions. Circulation. 2014 Jul 8;130(2):192-201
2: De Vis JB, Petersen ET, Bhogal A, Hartkamp NS, Klijn CJ, Kappelle LJ, Hendrikse J. Calibrated MRI to evaluate cerebral hemodynamics in patients with an internal carotid artery occlusion. J Cereb Blood Flow Metab. 2015 Jun;35(6):1015-23
3: Van der Kolk AG, Zwanenburg JJ, Brundel M, Biessels GJ, Visser F, Luijten PR, Hendrikse J. Distribution and natural course of intracranial vessel wall lesions in patients with ischemic stroke or TIA at 7.0 Tesla MRI. Eur Radiol. 2015 Jun;25(6):1692-700
4: De Rotte AA, Truijman MT, van Dijk AC, Liem MI, Schreuder FH, van der Kolk AG, de Kruijk JR, Daemen MJ, van der Steen AF, de Borst GJ, Luijten PR, Nederkoorn PJ, Kooi ME, van der Lugt A, Hendrikse J. Plaque components in symptomatic moderately stenosed carotid arteries related to cerebral infarcts: the plaque at RISK study. Stroke. 2015 Feb;46(2):568-71
5: Hendrikse J, Van der Grond J, Lu H, Van Zijl PCM, Golay X. Flow territory mapping of the cerebral arteries with MRI. Stroke. 2004;35:882-887

Side Activities

  • ZonMW Veni-subsidiereviewer 2018, 2019 en 2020 

     

Fellowship and Awards

  • 1: ERC-StG
    2: VENI and VIDI
    3: FP7-WP-Leader
    4: Dutch Heart Association
    5: STW/Technical Research Council

Research Output (279)

Contrast leakage distant from the hematoma in patients with spontaneous ICH:A 7 T MRI study

Jolink Wilmar MT, Lindenholz Arjen, van Etten Ellis S, van Nieuwenhuizen Koen M, Schreuder Floris Hbm, Kuijf Hugo J, van Osch Matthias Jp, Hendrikse Jeroen, Rinkel Gabriel Je, Wermer Marieke JH, Klijn Catharina JM 1 mei 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40 , p. 1002-1011 10 p.

Intracranial atherosclerosis assessed with 7-T MRI:Evaluation of patients with ischemic stroke or transient ischemic attack

Lindenholz Arjen, van der Kolk Anja G., van der Schaaf Irene C., van der Worp H. Bart, Harteveld Anita A., Dieleman Nikki, Bots Michiel L., Hendrikse Jeroen apr 2020, In: Radiology. 295 , p. 162-170 9 p.

Timing of procedural stroke and death in asymptomatic patients undergoing carotid endarterectomy:individual patient analysis from four RCTs

Poorthuis M H F, Bulbulia R, Morris D R, Pan H, Rothwell P M, Algra A, Becquemin J-P, Bonati L H, Brott T G, Brown M M, Calvet D, Eckstein H-H, Fraedrich G, Gregson J, Greving J P, Hendrikse J, Howard G, Jansen O, Mas J-L, Lewis S C, de Borst G J, Halliday A, 12 mrt 2020, In: British Journal of Surgery. 107 , p. 662-668 7 p.

Low interrater reliability of brachial plexus MRI in chronic inflammatory neuropathies

van Rosmalen Marieke H J, Goedee H Stephan, van der Gijp Anouk, Witkamp Theo D, Froeling Martijn, Hendrikse Jeroen, van der Pol W Ludo 3 feb 2020, In: Muscle & Nerve. 61 , p. 779-783 5 p.

Intracranial Atherosclerotic Burden on 7T MRI Is Associated with Markers of Extracranial Atherosclerosis:The SMART-MR Study

Zwartbol M. H. T., Geerlings M. I., Ghaznawi R., Hendrikse J., van der Kolk A. G., Asselbergs F. W., Nathoe H. M., de Borst G. J., Bots M. L., Emmelot M. H., de Jong P. A., Leiner T., Lely A. T., van der Kaaij N. P., Kappelle L. J., Ruigrok Y. M., Verhaar M. C., Visseren F. L. J., Westerink J., 5 dec 2019, In: American Journal of Neuroradiology. 40 , p. 2016-2022 7 p.

Subarachnoid Hemorrhage and Cerebral Perfusion Are Associated with Brain Volume Decrease in a Cohort of Predominantly Mild Traumatic Brain Injury Patients

van der Kleij Lisa A, De Vis Jill B, Restivo Matthew C, Turtzo L Christine, Hendrikse Jeroen, Latour Lawrence L 5 dec 2019, In: Journal of Neurotrauma. 37 , p. 600-607 8 p.

Associations of Perioperative Variables With the 30-Day Risk of Stroke or Death in Carotid Endarterectomy for Symptomatic Carotid Stenosis

Knappich Christoph, Kuehnl Andreas, Haller Bernhard, Salvermoser Michael, Algra Ale, Becquemin Jean Pierre, Bonati Leo H., Bulbulia Richard, Calvet David, Fraedrich Gustav, Gregson John, Halliday Alison, Hendrikse Jeroen, Howard George, Jansen Olav, Malas Mahmoud B., Ringleb Peter A., Brown Martin M., Mas Jean Louis, Brott Thomas G., Morris Dylan R., Lewis Steff C., Eckstein Hans Henning 1 dec 2019, In: Stroke. 50 , p. 3439-3448 10 p.

European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)

Düzel Emrah, Acosta-Cabronero Julio, Berron David, Biessels Geert Jan, Björkman-Burtscher Isabella, Bottlaender Michel, Bowtell Richard, Buchem Mark V, Cardenas-Blanco Arturo, Boumezbeur Fawzi, Chan Dennis, Clare Stuart, Costagli Mauro, de Rochefort Ludovic, Fillmer Ariane, Gowland Penny, Hansson Oskar, Hendrikse Jeroen, Kraff Oliver, Ladd Mark E, Ronen Itamar, Petersen Esben, Rowe James B, Siebner Hartwig, Stoecker Tony, Straub Sina, Tosetti Michela, Uludag Kamil, Vignaud Alexandre, Zwanenburg Jaco, Speck Oliver dec 2019, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11 , p. 538-549 12 p.

Intracranial Vessel Wall Magnetic Resonance Imaging Does Not Allow for Accurate and Precise Wall Thickness Measurements:An Ex Vivo Study

van Hespen Kees M., Zwanenburg Jaco J.M., Harteveld Anita A., Luijten Peter R., Hendrikse Jeroen, Kuijf Hugo J. 1 okt 2019, In: Stroke. 50 , p. e283-e284

Magnetic resonance imaging of the cervical spinal cord in spinal muscular atrophy

Stam Marloes, Haakma Wieke, Kuster Lidy, Froeling Martijn, Philippens Marielle E P, Bos Clemens, Leemans Alexander, Otto Louise A M, van den Berg Leonard H, Hendrikse Jeroen, van der Pol W Ludo 3 sep 2019, In: Neuroimage: Clinical [E]. 24 9 p.

All Research Output (279)