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prof. dr. F.W. (Folkert) Asselbergs

prof. dr. F.W. (Folkert) Asselbergs

Full Professor
prof. dr. F.W. (Folkert) Asselbergs
  • Division of Heart & Lungs

Biography

Biography

Prof Dr. Folkert W. Asselbergs is Professor of Precision medicine at Institute of Health Informatics and the institute of Cardiovasculair Science, University College London, Director of the NIHR BRC UCL/UCLH Clinical and Research Informatics Unit, consultant cardiologist and Professor of Precision Medicine at University Medical Center Utrecht, University of Utrecht, the Netherlands, associate editor European Heart Journal, section digital health and innovation, Chair Center for Circulatory Health, UMC Utrecht, and chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliance.nl). 

 

Professor Asselbergs published more than 500 scientific papers in the field of cardiovascular disease and his work has been funded by the Netherlands Heart Foundation, Netherlands Heart Institute, British Heart Foundation, leDucq Foundation, EU FP7, European Society of Cardiology, BBMRI, National Institutes of Health, Innovative Medicines Initiative, European Research Area Network on Cardiovascular Diseases and ZonMw.

 

His research program in complex genetics focuses on the discovery of genes influencing susceptibility to cardiovascular disease; the application of these findings for the validation of drug targets; and the use of genetic tests for treatment targeting (stratified medicine). Lately, he widened his research focus to precision medicine using linked data sources such as wearable information and routine care data obtained from electronic health records including free text. His ambition is to build a network for performing clinical trials within routine health care linked to national registries. 

 

Prof Asselbergs is member of a large number of consortia and (co-) founded several consortia of which igenetrain (www.igenetrain.net), and GENIUS-CHD (www.genius-chd.org), and CAPACITY-COVID ( https://capacity-covid.eu)  are the most prominent and recent ones. He is scientific coordinator of European IMI Bigdate@heart consortium (www.bigdata-heart.eu). Bigdata@heart aims to deliver clinically relevant disease cardiovascular phenotypes, scalable insights from real-world evidence including data from registries, wearables and electronic health records, and insight driving drug development and personalized medicine through advanced big-data analytics. 

 

Side Activities

  • Prof of Precision medicine at the Institute of Cardiovascular Science and Institute of Health Informatics, University College London
  • Director NIHR BRC Clinical Research Informatics Unit, University College London Hospital
  • Chair Center for Circulatory Health, UMC Utrecht
  • Chair data infrastructure Dutch Cardiovascular Alliance (www.dcvalliane.nl)
  • Associate editor European Heart Journal, section Digital Health and Innovation

Fellowship and Awards

2003 Dr. E. Dekker Scholarship of the Dutch Heart Foundation (2003T010).
2005 Scholarship Netherlands Heart Institute for postdoc Harvard School of public health
2007 Netherlands Foundation of CardioVascular Excellence grant
2010 Clinical fellowship from the Netherlands Organisation for Health Research (ZonMw grant 90700342),
2012 European Society of Cardiology Training grant (T2012-006).
2013 Fellow European Society of Cardiology
2014 Dr. E. Dekker Scholarship of the Dutch Heart Foundation (2014T001)
2019 Scholarship European Society of Cardiology Executive Master Health Economics at LSE
2021 Pearl award ZonMw, Netherlands: www.zonmw.nl/nl/actueel/parelprojecten/parel-voorbruggenbouwer-in-hartfalen-onderzoek/

Research Output (525)

Effect of tissue-grouped regulatory variants associated to type 2 diabetes in related secondary outcomes

Hemerich Daiane, Smit Roelof A J, Preuss Michael, Stalbow Lauren, van der Laan Sander W, Asselbergs Folkert W, van Setten Jessica, Tragante Vinicius Dec 2023, In: Scientific Reports. 13

Identification of novel genetic risk factors of dilated cardiomyopathy:from canine to human

Niskanen Julia E, Ohlsson Åsa, Ljungvall Ingrid, Drögemüller Michaela, Ernst Robert F, Dooijes Dennis, van Deutekom Hanneke W M, van Tintelen J Peter, Snijders Blok Christian J B, van Vugt Marion, van Setten Jessica, Asselbergs Folkert W, Petrič Aleksandra Domanjko, Salonen Milla, Hundi Sruthi, Hörtenhuber Matthias, Kere Juha, Pyle W Glen, Donner Jonas, Postma Alex V, Leeb Tosso, Andersson Göran, Hytönen Marjo K, Häggström Jens, Wiberg Maria, Friederich Jana, Eberhard Jenny, Harakalova Magdalena, van Steenbeek Frank G, Wess Gerhard, Lohi Hannes, Dec 2023, In: Genome Medicine. 15 21 p.

The added value of abnormal regional myocardial function for risk prediction in arrhythmogenic right ventricular cardiomyopathy

Kirkels Feddo P, Rootwelt-Norberg Christine, Bosman Laurens P, Aabel Eivind W, Muller Steven A, Castrini Anna I, Taha Karim, van Osta Nick, Lie Øyvind H, Asselbergs Folkert W, Lumens Joost, Te Riele Anneline S J M, Hasselberg Nina E, Cramer Maarten J, Haugaa Kristina H, Teske Arco J 23 Nov 2023, In: European heart journal. Cardiovascular Imaging. 24 , p. 1710-1718 9 p.

Urbanization gradient, diet, and gut microbiota in Sub-Saharan Africa:a systematic review

Paulo Linda Simon, Msema Bwire George, Klipstein-Grobusch K., Kamuhabwa Appolinary, Kwesigabo Gideon, Chillo Pilly, Asselbergs Folkert W., Lenters Virissa C. 12 Sep 2023, In: Frontiers in Microbiomes. 2

Monitoring of Myocardial Involvement in Early Arrhythmogenic Right Ventricular Cardiomyopathy Across the Age Spectrum

Kirkels Feddo P, van Osta Nick, Rootwelt-Norberg Christine, Chivulescu Monica, van Loon Tim, Aabel Eivind W, Castrini Anna I, Lie Øyvind H, Asselbergs Folkert W, Delhaas Tammo, Cramer Maarten J, Teske Arco J, Haugaa Kristina H, Lumens Joost 29 Aug 2023, In: Journal of the American College of Cardiology. 82 , p. 785-797 13 p.

Locational memory of macrovessel vascular cells is transcriptionally imprinted

Spanjersberg Talitha C F, Oosterhoff Loes A, Kruitwagen Hedwig S, van den Dungen Noortje A M, Vernooij Johannes C M, Asselbergs Folkert W, Mokry Michal, Spee Bart, Harakalova Magdalena, van Steenbeek Frank G 10 Aug 2023, In: Scientific Reports. 13

Survival after HeartMate 3 left ventricular assist device implantation:real-world data from Europe

Numan Lieke, Schramm Rene, Oerlemans Marish I F J, van der Kaaij Niels P, Aarts Emmeke, Ramjankhan Faiz Z, Oppelaar Anne-Marie, Morshuis Michiel, Guenther Sabina P W, Zimpfer Daniel, Riebandt Julia, Wiedemann Dominik, Asselbergs Folkert W, Van Laake Linda W Aug 2023, In: ESC heart failure. 10 , p. 2754-2756 3 p.

Exercise does not influence development of phenotype in PLN p.(Arg14del) cardiomyopathy

van Lint Freyja H M, Hassanzada Fahima, Verstraelen Tom E, Wang Weijia, Bosman Laurens P, van der Zwaag Paul A, Oomen Toon, Calkins Hugh, Murray Brittney, Tichnell Crystal, Beuren Thais M A, Asselbergs Folkert W, Houweling Arjan, van den Berg Maarten P, Wilde Arthur A M, James Cynthia A, van Tintelen J Peter Aug 2023, In: Netherlands Heart Journal. 31 , p. 291-299 9 p.

Individualized Family Screening for Arrhythmogenic Right Ventricular Cardiomyopathy

Muller Steven A, Gasperetti Alessio, Bosman Laurens P, Schmidt Amand F, Baas Annette F, Amin Ahmad S, Houweling Arjan C, Wilde Arthur A M, Compagnucci Paolo, Targetti Mattia, Casella Michela, Calò Leonardo, Tondo Claudio, van der Harst Pim, Asselbergs Folkert W, van Tintelen J Peter, Oerlemans Marish I F J, Te Riele Anneline S J M 18 Jul 2023, In: Journal of the American College of Cardiology. 82 , p. 214-225 12 p.

Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF):a randomised clinical trial

Brugts Jasper J., Radhoe Sumant P., Clephas Pascal R.D., Aydin Dilan, van Gent Marco W.F., Szymanski Mariusz K., Rienstra Michiel, van den Heuvel Mieke H., da Fonseca Carlos A., Linssen Gerard C.M., Borleffs C. Jan Willem, Boersma Eric, Asselbergs Folkert W., Mosterd Arend, Brunner-La Rocca Hans Peter, de Boer Rudolf A., Emans M. E., Beeres S. L.M.A., Heerebeek L., Kirchhof C., Van Ramshorst J., Spee R., Smilde T., Van Eck M., Kaplan E., Hazeleger R., Tukkie R., Feenema M., Kok W., Van Halm V., Handoko M. L., Van Kimmenade R., Post M., Van Mieghem N., Manintveld O. C., 24 Jun 2023, In: The Lancet. 401 , p. 2113-2123 11 p.

All research output

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